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The Q-Symbio Study was the first randomized, double-blind, placebo-controlled study that had a large enough sample (420 heart failure patients), a sufficient dosage of Coenzyme Q10 (3 times 100 milligram per day), and a long enough follow-up period (106 weeks) to test the effectiveness of Coenzyme Q10 adjunctive therapy on major adverse cardiovascular events and mortality in heart failure
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[1] Tirzepatide may cause fetal harm and should be discontinued at least 2 months before a planned pregnancy