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Recommended Dosage and Frequency After Bariatric Surgery The UK BNF standard regimen for confirmed B12 deficiency is 1 mg hydroxocobalamin IM on alternate days for two weeks, then 1 mg every three months

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If your body lacks sufficient B12 due to dietary reasons (e.g., you’re vegan and not supplementing) or, more commonly, due to an inability to absorb B12 from your gut (e.g., pernicious anaemia, certain stomach conditions, or medications), then replenishing those levels with an injection will directly address the cause of your fatigue